Table 3. Univariate and multivariate Cox proportional hazards regression of tumour characteristics for sarcoma-specific survival.

		Univariate		Multivariate
Characteristic	N (%)	HR (95% CI)	P	HR (95% CI)	P
Tumour size (cm)
⩽5	153 (52)	1		1.10 (1.05–1.15)a	<0.0001
5–10	93 (32)	3.09 (1.73–5.52)	<0.0001
>10	48 (16)	8.24 (4.60–14.75)	<0.0001
Necrosis
No	153 (52)	1		1
Yes	141 (48)	3.86 (2.34–6.39)	<0.0001	1.60 (0.88–2.90)	0.12
Vascular invasion
No	255 (87)	1		1
Yes	39 (13)	2.80 (1.67–4.70)	<0.0001	1.60 (0.93–2.75)	0.09
Histological grade
1	12 (4)	NAb		1.57 (1.11–2.22)c	0.01
2	71 (24)	1
3	103 (35)	3.10 (1.36–7.09)	0.007
4	108 (37)	5.16 (2.31–11.52)	<0.0001
Tumour depth
Superficial	109 (37)	1		1
Deep	185 (63)	5.54 (2.76–11.11)	<0.0001	3.51(1.71–7.38)	0.001
Location
Extremity	202 (69)	1		1
Axis of body	92 (31)	1.13 (0.70–1.83)	0.61	1.65 (1.01–2.68)	0.04

Abbreviations: HR=hazard ratio; CI=confidence interval; NA=not available.

^aper centimetre.

^bgrade 1 tumours excluded from the analysis due to zero events.

^cper grade.