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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Methods Enzymol. 2012;502:273–290. doi: 10.1016/B978-0-12-416039-2.00014-8

Figure 2.

Figure 2

Three-dimensional structure of the human RI·RNase 1 complex (Protein Data Bank entry 1z7x). The active-site histidine residues 12 and 119 of RNase 1 are depicted explicitly, and the N and C termini of RI are labeled. The complex has Kd = 2.9 × 10−16 M (Johnson et al., 2007b).