Table 1.

Theoretical numbers of amino-acid residues potentially involved in silica binding through diazo-coupling (Tyrosine, Y), EDC/NHS activation (diazo-Y, Aspartic and Glutamic acid residues, D and E) and unmodified basic amino-acids residues (Arginine, R, Histidine, H and Lysine, K) in silk.

	Heavy chaina		Light Chainb		Silk proteinc
	Nb of residues	%	Nb of residues	%	Nb of residues	%
Diazo modified AA (Y)	277	5.30	11	4.2	288*	5.26
Acid AA (D, E)	55	1.05	22	8.39	77*	1.41
Unmodified AA (R, H, K)	31	0.59	21	8.01	52	0.95
Total AA	5209	100	262	100	5471	100

^aHa et al. ³¹

^bKikuchi et al. ³³

^cInoue et al. ³²

^*EDC/ NHS activation: potential reactive amino-acids for peptide coupling onto silk