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Serum interferon-α in patients with SLE stratified by UBE2L3 rs5754217 genotype. A. African American patients with SLE. B. European American patients with SLE. Serum IFN-α activity is shown on the Y-axis. Lines indicate the median and error bars show the interquartile range. P values were calculated using the Mann-Whitney U test, comparing TT genotype to the GG and GG genotypes (recessive model).
