Table 1.
HAT | Affected | Mutation | Relative | p value | n | HAT mutation; | Htt | HAT mutation; | No |
---|---|---|---|---|---|---|---|---|---|
family | gene | eclosion, % | Htt exp. | exp. | no Htt | Htt | |||
CBP/p300 | nej | nej3 | 67.3 | <0.01 | 1,268 | 150 | 209 | 469 | 440 |
MYST | enok | enok2 | 92.5 | 0.47 | 2,341 | 202 | 208 | 989 | 942 |
mof | mof2 | 100.5 | 0.96 | 1,437 | 232 | 206 | 528 | 471 | |
CG1894 | Df(3R)Ex6259 | 83.7 | 0.12 | 1,432 | 197 | 215 | 533 | 487 | |
GNAT | Pcaf | PcafE333St | 49.4 | <0.001 | 3,419 | 114 | 215 | 1,600 | 1,490 |
Df(3L)iro-2 | 54 | <0.001 | 4,163 | 340 | 612 | 1,629 | 1,582 | ||
UAS-Pcaf1 | 102.2 | 0.89 | 1,002 | 99 | 88 | 427 | 388 | ||
UAS-Pcaf3B | 118.4 | 0.3 | 785 | 109 | 93 | 290 | 293 | ||
UAS-Pcaf5L | 135.5 | 0.08 | 867 | 89 | 74 | 331 | 373 | ||
UAS-Pcaf7 | 126.2 | 0.32 | 390 | 51 | 46 | 137 | 156 |
The relative eclosion rates, statistical significance, number of all scored progenies (n) and the number of offspring in the four genotype categories are shown for loss of function HAT mutants, HAT deletions and UAS-Pcaf overexpressor lines.