Skip to main content
. 2012 Jan 25;46(1):38–46. doi: 10.1159/000335099

Table 3.

Heritability and genetic correlation of PFS and SMS caries scores

Phenotype n PFS SMS Shared genetics



h2 SE pa R2 h2 SE pb R2 rhoG SE prhoG=0c prhoG=1d
Primary dentition
  dfs 953 0.34 0.10 3 × 10−4 0.01 0.42 0.10 2 × 10−5 0.00 0.76 0.08 0.001 9 × 10−4
  Proportion dfs 953 0.53 0.11 2 × 10−6 0.04 0.42 0.10 2 × 10−5 0.00 0.93 0.08 5 × 10−6 0.208
Permanent dentition
  DMFS 1,939 0.27 0.06 7 × 10−6 0.35 0.27 0.07 2 × 10−4 0.22 1.00 2 × 10−6 1.000
  Proportion DMFS 1,939 0.37 0.06 2 × 10−11 0.33 0.21 0.06 2 × 10−4 0.21 0.98 0.08 5 × 10−9 0.424
Total dentition
  dfs + DMFS 2,378 0.19 0.04 2 × 10−6 0.28 0.17 0.04 1 × 10−5 0.17 1.00 1 × 10−7 1.000
  Proportion dfs + DMFS 2,378 0.31 0.04 2×10−13 0.35 0.23 0.04 2 × 10−8 0.19 0.99 0.06 6 × 10−13 0.422

h2 = Residual heritability after adjusting for sex and age; SE = standard error, not applicable for models that converged at rhoG = 1.00; R2 = proportion of trait variance attributable to sex and age; rhoG = genetic correlation, i.e. a measure of the extent to which traits covary due to genes.

a p value that PFS caries is heritable.

b p value that SMS caries is heritable.

c p value that shared genetic risk factors affect both PFS and SMS.

d p value that unshared genetic risk factors differentially affect PFS and SMS.