Table 3.
Effect of blood count on Alu and LINE-1 methylation (combined analysis of the five studies)
| Blood count | Alu |
LINE-1 |
||
|---|---|---|---|---|
| N | β (95% CI)a | N | β (95% CI)a | |
| White blood cells, 103cells/mm3 | 1013 | 0.001 (−0.060 to 0.062) | 991 | 0.077 (−0.034 to 0.187) |
| Neutrophils, % | 939 | 0.008 (−0.006 to 0.022) | 917 | 0.036 (0.010 to 0.061) |
| Lymphocytes, % | 1001 | −0.009 (−0.023 to 0.006) | 979 | −0.038 (−0.065 to −0.012) |
| Monocytes, % | 994 | 0.001 (−0.040 to 0.042) | 972 | −0.032 (−0.105 to 0.042) |
| Eosinophils, % | 932 | −0.012 (−0.070 to 0.047) | 910 | 0.010 (−0.094 to 0.114) |
| Basophils, % | 932 | 0.008 (−0.254 to 0.270) | 910 | −0.198 (−0.668 to 0.272) |
aAdjusted for age, gender, alcohol drinking and study.