Figure 4.

DNA methylation levels in nuclear-encoded mitochondrial genes in a control population. Twenty-four healthy female adult samples were analysed for genome-wide methylation using Illumina® HumanMethylation27 arrays. Probes were assigned to ‘non-mitochondrial’ or ‘mitochondrial’ groups as described in the main text. Histogram shows the DNA methylation distribution of CpG island probes assigned to non-mitochondrial or mitochondrial groups