Table 1.

Frequency of IRF5 haplotypes in lupus patients and healthy controls. Haplotype frequencies observed in controls and systemic lupus erythematosus (SLE) patient cohort at single-nucleotide polymorphisms rs2004640 (T : risk, G: protective) and rs10954213 (A: risk, G: protective).

Haplotype	Allele 1	Allele 2	Frequency (patients) n = 1390	Frequency (controls) n = 2039	SLE risk
1	TA	TA	0.2576	0.1947	Risk/risk
2	TA	TG	0.4460	<0.0001	Risk/neutral
3	GA	GG	0.2108	0.2737	Protective/protective
4	GG	TG	0.0165	0.1810	Protective/neutral