Table 1.
Variable | All (n=23) mean(SD)/N(%) |
Stable MCI (n=17) | Converted to AD (n=6) | p-value |
---|---|---|---|---|
| ||||
mean(SD)/N(%) | mean(SD)/N(%) | |||
Age (yrs) | 75.6 (5.5) | 74.5 (5.8) | 78.7 (2.9) | 0.112 |
Female | 7 (30.4%) | 5 (29.4%) | 2 (33.3%) | 0.618 |
Education (yrs) | 15.6 (3.1) | 15.3 (3.1) | 16.3 (3.4) | 0.497 |
APOE E4 allele | 10/22 (45.5%) | 9/16 (56.3%) | 1/6 (16.7%) | 0.162 |
Dementia Med | 4/22 (18.2%) | 2/16 (12.5%) | 2/6 (33.3%) | 0.292 |
CDR-Sum | 1.3 (0.8) | 1.2 (0.8) | 1.7 (0.7) | 0.229 |
MMSE | 26.7 (2.1) | 27.2 (2.0) | 25.0 (1.3) | 0.018 |
Memory Z-score | −2.0 (1.2) | −1.5 (1.0) | −3.2 (0.3) | 0.001 |
CVLT-total | 34.2 (12.9) | 38.6 (12.1) | 22.5 (5.5) | 0.006 |
CVLT-sdfr | 5.4 (3.7) | 7.1 (2.6) | 0.7 (0.8) | <0.001 |
CVLT-ldfr | 5.5 (3.9) | 6.8 (3.5) | 1.8 (2.3) | 0.004 |
Wechsler-Imm | 8.2 (3.1) | 8.8 (3.3) | 6.5 (1.8) | 0.128 |
Wechsler-Del | 6.0 (4.2) | 7.1 (4.1) | 2.8 (2.7) | 0.031 |
GDS | 1.5 (1.2) | 1.5 (1.1) | 1.2 (1.6) | 0.609 |
Abbreviations: MCI=amnestic mild cognitive impairment; AD=Alzheimer’s disease; CDR-Sum = Clinical Dementia Rating, Sum of Boxscores; MMSE=Mini-mental State Examination; CVLT=California Verbal Learning Test; GDS=15-item Geriatric Depression Scale
Fischer’s Exact test for categorical variables; Students t-test for continuous variables