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. 2012 Mar 15;7(3):e33249. doi: 10.1371/journal.pone.0033249

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(A–C) Quantification of histone PTM regulation in hippocampal regions CA1 (A), CA3 (B), and DG (C) in Y, AU and AI rats with (Activated) or without (Baseline) immediately preceding RPC training. Representative western blots are organized according to the corresponding quantitative results. Histone modifications were normalized to pan-histone H3 and group data are represented as the percentage of young baseline values. Error bars = S.E.M. Number signs and asterisks denote statistically significant experience- and age-dependent effects, respectively (p<0.05).