Table 3. Averaged net changes (from reactants to products) of some properties associated with polarity for anaerobic and aerobic reaction pairs.

Descriptors	Characterization	Averaged net changes
		Anaerobic reaction pair	Aerobic reaction pair
AlogP98a	Logarithm of partition coefficient, atom-type value, using latest parameters	0.31	−0.14
PSAb	Polar molecular surface area	−20.85	7.12
PVb	Polar molecular volume	−25.82	5.95
Acceptorb	H-bond acceptor count	−0.82	0.42
Donorb	H-bond donor count	−0.43	0.18

^acalculated with Cerius2.

^bcalculated with Sybyl 7.0.