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. 2012 Mar 15;7(3):e33780. doi: 10.1371/journal.pone.0033780

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Lundström et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Sum of 15-LOX metabolites from both ω-3 and ω-6 pathways. (B) Sum of 15-LOX metabolites from ω-6 fatty acids (12-and 15-HETE, 15-KETE, 5,15-DiHETE, 13-HODE, 9,10,13- and 9,12,13-TriHOME, 9-HODE, 9-KODE and 15-HETrE), (C) Sum of 15-LOX metabolites from ω-3 fatty acids (9- and 13-HOTE, 12- and 15-HEPE and 17-HDoHE). Data are provided as concentration in BALF (pM). HC: Healthy controls, AC: Asthmatic controls, AFP: Asthmatics following provocation. The p-values obtained using Student's T-test (HC vs. AC and HC vs. AFP) and one-sided Cochran-Armitage trend test (HC, AC and AFP) are indicated in the figure.