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. 2012 Mar 15;8(3):e1002424. doi: 10.1371/journal.pcbi.1002424

Figure 1. Intrinsic excitability of neurons introduces timing errors.

Figure 1

A. Diagram of elements used in the numerical simulations. B. Computed traces for a single model neuron with a value of gKHT of 0.1 or 0.7 µS showing presynaptic voltage waveforms and postsynaptic currents at the onset of a 300 Hz or 900 Hz stimulus train. Errors in timing are apparent at 300 Hz with gKHT = 0.7 µS (asterisk). At 900 Hz, the neuron with gKHT = 0.1 µS fires only a single action potential at the onset of the train. C. A plot of the vector strength PE for this neuron with gKHT equal to 0.1 or 0.7 µS as a function of stimulus frequency.