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Logistic regression model from personal and cancer family history characteristics associated with MLH1 or MSH2 pathogenic mutation
| Variable | Category | OR | 95%CI | p-value |
|---|---|---|---|---|
| CRC location (proband) | Distal | 1 | ||
| Proximal | 3.616 | 1.185-11.037 | 0.024 | |
| CRC Histological Type | Tubular Adenocarcinoma | 1 | ||
| Mucinous Adenocarcinoma | 3.974 | 1.160-13.613 | 0.028 | |
| Number of CRCs* | 1.544 | 1.172-2.033 | 0.002 |
*Based on family history, considered as discrete variable
