Table 9.
Logistic regression model from personal and cancer family history characteristics associated with MLH1 or MSH2 pathogenic mutation
Variable | Category | OR | 95%CI | p-value |
---|---|---|---|---|
CRC location (proband) | Distal | 1 | ||
Proximal | 3.616 | 1.185-11.037 | 0.024 | |
CRC Histological Type | Tubular Adenocarcinoma | 1 | ||
Mucinous Adenocarcinoma | 3.974 | 1.160-13.613 | 0.028 | |
Number of CRCs* | 1.544 | 1.172-2.033 | 0.002 |
*Based on family history, considered as discrete variable