Table 1.
List of candidate biomarker proteins found at higher abundance in prostatitis compared to control, according to spectral counting.
| Gene Name | Average Spectral Count | Fold Change* | Prostatic Origin** | |
|---|---|---|---|---|
| Control | Prostatitis | |||
| ALB | 1441 | 3079 | 2.1 | |
| SERPINA1 | 149 | 382 | 2.6 | Yes |
| CST4 | 83 | 468 | 5.7 | |
| CST3 | 65 | 202 | 3.1 | Yes |
| PAEP cDNA FLJ52183 | 52 | 144 | 2.8 | |
| C4A | 38 | 131 | 3.5 | Yes |
| A2M | 44 | 103 | 2.3 | Yes |
| SERPINA5 | 37 | 122 | 3.3 | |
| C3 | 34 | 104 | 3 | Yes |
| LPL | 30 | 66 | 2.2 | |
| IGHG2 | 17 | 46 | 2.6 | |
| A1BG | 25 | 50 | 2 | |
| MSLN | 16 | 33 | 2 | |
| SERPING1 | 17 | 48 | 2.9 | |
| SCPEP1 | 17 | 44 | 2.6 | Yes |
| GLA | 21 | 43 | 2 | Yes |
| OLFM4 | 15 | 41 | 2.7 | Yes |
| SMPD1 | 9 | 20 | 2.2 | Yes |
| CTSF | 9 | 24 | 2.5 | Yes |
| SERPINF1 | 10 | 33 | 3.4 | Yes |
| MINPP1 | 9 | 19 | 2.1 | Yes |
| CFI | 9 | 18 | 2.1 | |
| CTSC | 5 | 10 | 2.2 | |
| CST6 | 7 | 15 | 2.2 | Yes |
| TXNDC16 | 8 | 18 | 2.3 | Yes |
| LCN1 | 2 | 15 | 6.3 | |
| COL6A2 | 3 | 15 | 5.5 | Yes |
| A4GALT | 4 | 15 | 4 | Yes |
| PATE4 | 4 | 13 | 3 | Yes |
| TIMP3 | 5 | 11 | 2.1 | |
| CST2 | 2 | 16 | 9.6 | |
| FGB | 4 | 11 | 2.6 | |
| COMP | 4 | 12 | 2.9 | |
* Fold change = average prostatitis/average control
** Protein/gene name annotated as expressed in the prostate in at least 2 out of 3 databases (BioGPS; Unigene, Protein Atlas)