Table 1.
Characteristics of the individuals included in the replication stages of the study.
| PATIENTS WITH IDIOPATHIC DVT | CONTROLS | |
|---|---|---|
| n= | 719 | 719 |
| GEOGRAPHIC ORIGIN, n (%) | ||
| Lombardy | 453 (63) | 490 (67) |
| Northern Italy other than Lombardy | 89 (13) | 84 (12) |
| Central Italy | 30 (4) | 20 (3) |
| Southern Italy and islands | 109 (15) | 107 (15) |
| Not available | 38 (5) | 18 (3) |
| MALE GENDER, n (%) | 325 (45) | 325 (45) |
| AGE, mean years (standard deviation) | 42.5 (15) | 42.5 (14) |
| PULMONARY EMBOLISM, n (%) | 148 (20) | / |
| REFERRED FOR MORE THAN ONE EPISODE, n (%) | 167 (23) | / |
| BODY MASS INDEX, kg/m2 | 25.9 (4.7) | 24 (4) |
| FACTOR V LEIDEN (rs6025) GENOTYPE, n (%) | ||
| GG | 611 (85) | 696 (97) |
| AG | 102 (14) | 23 (3) |
| AA | 6 (1) | 0 |
| PROTHROMBIN G20210A (rs1799963) GENOTYPE, n (%) | ||
| GG | 654 (91) | 695 (97) |
| AG | 63 (8) | 24 (3) |
| AA | 2 (1) | 0 |
| NATURAL ANTICOAGULANT DEFICIENCIES, n (%) | ||
| Antithrombin | 22 (3) | 2 (0.2) |
| Protein C | 26 (3) | 2 (0.2) |
| Protein S | 30 (4) | 10 (1) |
| LABORATORY MEASUREMENTS, mean (standard deviation) | ||
| Antithrombin,% | 97 (12) | 99 (15) |
| Protein C, % | 102 (27) | 105 (22) |
| Protein S, % | 105 (30) | 111 (31) |
| Prothrombin time, international normalized ratio | 1 (0.16) | 0.99 (0.15) |
| Activated partial thromboplastin time, ratio | 1 (0.1) | 1 (0.1) |
| Coagulation factor VIII coagulant activity, % | 142 (39) | 114 (30) |
| Fibrinogen coagulant activity, % | 304 (72) | 291 (63) |