Table 3.

The severe AD profile query correlates with other neurodegenerative condition transcriptional changes.

Huntington's disease in various brain regions
	Caudate nucleus		Cerebellum		Frontal cortex
	r	N	r	N	r	N
severe	0.85	315	0.72	113	0.78	101
moderate	0.73	290	0.39	92	0.22	66
incipient	0.33	124	0.39	48	0.17	44
PD in various brain regions
	SFG		LSN		MSN
	r	N	r	N	r	N
severe	0.88	85	0.77	127	0.82	154
moderate	0.61	74	0.70	104	0.55	134
incipient	0.43	34	0.21	46	0.12	52
Down's Syndrome				Bipolar Disorder
	r	N			r	N
severe	0.58	161		severe	0.87	139
moderate	0.68	202		moderate	0.58	73
incipient	0.04	112		incipient	0.03	44

The correlation scores with the severe AD profile are shown for four distinct neurodegenerative conditions: Huntington's disease, Parkinson's disease, Down's syndrome and Bipolar disorder.