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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 Mar 23;4(7):1073–1083. doi: 10.1158/1940-6207.CAPR-10-0333

Figure 4.

Figure 4

Exogenous miR-101 suppresses proliferation and growth of prostate cancer cells in vitro and in vivo. Cell proliferation and cell viability of cultured BPH1CmiR101 and BPH1Cvec cell lines were compared under light microscope (A), colony formation assay (B), and MTT assay (C). The results from colony formation and MTT assays represented the mean ± SD of 2 independent experiments with triplicates. D, comparison of tumor xenograft growth between BPH1CmiR101 and BPH1Cvec groups. The day of cell inoculation was the experimental start day and all mice were sacrificed on day 36. The growth of solid tumor xenografts was monitored every other day and measured using vernier calipers. E, The tumor mass (g) was measured on the final experiment day immediately after the tumor tissue was removed from the mouse by surgical excision. The average tumor mass is indicated as a bold bar in each group. The P value was compared with vector control BPH1Cvec group, *, P < 0.05.