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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Thromb Res. 2011 Nov 30;130(4):629–635. doi: 10.1016/j.thromres.2011.11.010

Figure 1.

Figure 1

Diagrammatic representation of procedures comprising the rabbit aorta thrombus model. Sequentially, these procedures include 1) denudation of the abdominal aorta, using an embolectomy catheter introduced into the right femoral artery; 2) measurement of baseline abdominal aortic flow by spectral Doppler echocardiography; 3) induction of a thrombus by administration of 5% sodium ricinoleate and thrombin; 4) measurement of post-thrombotic flow distal to the thrombus; 5) introduction of thrombolytic preparation proximal to the thrombus, through a catheter introduced into the right carotid artery; 6) in rabbits receiving ultrasound treatment, transabdominal administration of color Doppler ultrasound for 2 minutes or intermittently for 30 minutes; and 7) spectral Doppler flow measurements every 2 minutes for 30 minutes.