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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Thromb Res. 2011 Nov 30;130(4):629–635. doi: 10.1016/j.thromres.2011.11.010

Figure 3.

Figure 3

Spectral Doppler flow measurements (expressed as % recanalization; see Methods text) distal to clots at 2-minute intervals following treatment administration. Each point is the mean of 2–5 determinations (due to technical inconsistencies in obtaining measurements for all time points); bars represent standard errors (S.E.; also calculated for the 0-time point). Filled circles are controls (0.02M phosphate-buffered saline, pH 7.4; PBS); filled triangles are free tissue plasminogen activator (tPA); filled squares are tPA mixed with Definity; open circles are tPA-loaded echogenic liposomes (TELIP). A, 0.2 MI (mechanical index) ultrasound applied for 30 minutes after treatment initiation; B, 0.4 MI ultrasound applied for 2 minutes after treatment initiation.