Table 1.

Effects of SAME on liver marker profile in rat

Treatment	AST U/l	ALT U/l	ALP U/l	LDH U/l	γ-GT U/l
Control (Saline, 0.9% NaCl)	83.3 ± 9.3A	34.3 ± 4.0A	246.7 ± 16.3A	50.8 ± 6.9A	69.8 ± 6.8A
GTM (100 mg/kg bw)	182.6 ± 18.3D	68.9 ± 8.0D	366.3 ± 26.7E	64.3 ± 7.0C	94.2 ± 8.8D
GTM + SAME (100 mg/kg bw)	148.9 ± 17.6C	63.8 ± 5.6C	311.3 ± 17.8D	59.5 ± 6.2B	84.6 ± 7.6C
GTM + SAME (200 mg/kg bw)	122.1 ± 10.6B	51.0 ± 6.9B	263.7 ± 19.0C	49.0 ± 4.8A	79.5 ± 6.8BC
SAME (200 mg/kg bw)	83.5 ± 6.8A	35.6 ± 5.9A	240.7 ± 13.8A	49.7 ± 6.3A	72.6 ± 7.3A

Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other

GTM, gentamicin; SAME, methanol extract of Sonchus asper