Table 2.

Effects of SAME on serum chemistry in rat

Treatment	Total protein (mg/dl)	Albumin (mg/dl)	Triglycerides (mg/dl)	Total cholesterol (mg/dl)	Total bilirubin (mg/dl)	Direct bilirubin (mg/dl)	Urea (mg/dl)	Creatinine (mg/dl)
Control (Saline, 0.9% NaCl)	42.5 ± 4.7A	22.7 ± 3.5A	12.8 ± 2.8A	6.8 ± 0.84A	1.51 ± 0.36A	0.87 ± 0.14A	33.5 ± 5.7A	0.78 ± 0.16A
GTM (100 mg/kg bw)	33.7 ± 3.7D	16.4 ± 2.3D	18.6 ± 2.0B	12.0 ± 2.95D	2.83 ± 0.45D	1.17 ± 0.44E	56.2 ± 6.6C	3.7 ± 0.60C
GTM + SAME (100 mg/kg bw)	35.7 ± 4.1C	18.4 ± 2.8C	17.2 ± 2.2B	10.1 ± 1.73CD	1.69 ± 0.34C	1.03 ± 0.16C	43.2 ± 5.2BC	2.6 ± 0.65B
GTM + SAME (200 mg/kg bw)	40.2 ± 5.6B	21.1 ± 3.2AB	13.1 ± 2.2A	8.8 ± 1.50B	1.67 ± 0.24C	0.97 ± 0.17B	40.6 ± 6.2B	1.2 ± 0.26A
SAME (200 mg/kg bw)	43.2 ± 4.2A	23.2 ± 2.9A	12.1 ± 1.4A	7.2 ± 1.69A	1.49 ± 0.36A	0.83 ± 0.16A	32.4 ± 4.6A	0.84 ± 0.32A

Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other.

GTM, gentamicin; SAME, methanol extract of Sonchus asper