Table 6.

Effects of SAME on hepatic TBARS, GSH and DNA fragmentation of rat

Treatment	TBARS (nM /mg protein)	GSH (μM/g tissue)	DNA fragmentation%
Control (Saline, 0.9% NaCl)	76.9 ± 3.0A	0.74 ± 0.02A	0.48 ± 0.08A
GTM (100 mg/kg bw)	137.4 ± 6.0D	0.48 ± 0.03D	1.34 ± 0.13D
GTM + SAME (100 mg/kg bw)	116.6 ± 5.4C	0.59 ± 0.03C	1.11 ± 0.10C
GTM + SAME (200 mg/kg bw)	104.9 ± 4.4B	0.68 ± 0.04B	0.88 ± 0.09B
SAME (200 mg/kg bw)	76.1 ± 4.1A	0.76 ± 0.03A	0.40 ± 0.08A

Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other.

GTM, gentamicin; SAME, methanol extract of Sonchus asper