Table 7.

Effects of SAME on renal TBARS, GSH and DNA fragmentation of rat

Treatment	TBARS (nM /mg protein)	GSH (μM/g tissue)	DNA fragmentation%
Control (Saline, 0.9% NaCl)	58.77 ± 6.4AB	0.82 ± 0.02A	0.21 ± 0.09A
GTM (100 mg/kg bw)	81.07 ± 7.92D	0.56 ± 0.03D	2.14 ± 0.11C
GTM + SAME (100 mg/kg bw)	70.48 ± 6.78C	0.67 ± 0.03C	1.62 ± 0.28C
GTM + SAME (200 mg/kg bw)	61.10 ± 5.82B	0.76 ± 0.04B	0.95 ± 0.14B
SAME (200 mg/kg bw)	59.62 ± 7.03AB	0.84 ± 0.03A	0.22 ± 0.04A

Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other.

GTM, gentamicin; SAME, methanol extract of Sonchus asper