Table 1. MFI for binding of anti-EGFR mAbs ICR10 and ICR16 to the EGFR-overexpressing HN5 and EGFRvIII-overexpressing (HC2 20d2/c) cell lines.
MFI
|
||
---|---|---|
Antibody | HN5 | HC220d2/c |
Control | 6.87 | 5.04 |
ICR10 | 1092.45 | 3.55 |
ICR16 | 1189.75 | 593.05 |
Abbreviations: EGFR=epidermal growth factor receptor; EGFRvIII=type-III deletion mutant form of EGFR; mAbs=monoclonal antibodies; MFI=mean fluorescence intensity.