Table 3. Lifetime ratesa of colorectal cancer incidence and mortality per 100 000 population, percentage of cases which would be detected by screening, surveillance and symptomatically, and percentage reductions in incidence and mortality compared with no screening, for core screening scenarios.

	Incidence
	Screen detected CRC		Surveillance-detected CRCb		Symptomatic CRC			Mortality
Scenario	Rate	% of cases	Rate	% of cases	Rate	% of cases	% reduction in CRC incidencec	CRC mortality rate	% reduction in CRC mortalityc
No screening	0	—	0	—	5158	100	—	2287	—
gFOBT at 55–74 years	695	13.6	11	0.2	4401	86.2	1.0	2016	11.8
FIT at 55–74 years	1313	29.8	78	1.8	3010	68.4	14.7	1465	36.0
FSIG once at 60 years	138	2.8	25	0.5	4742	96.7	4.9	2116	7.5

Abbreviations: CRC=colorectal cancer; FIT=faecal immunochemical test; FSIG=flexible sigmoidoscopy; gFOBT=guaiac-based faecal occult blood test.

^aOver the entire lifetime of the cohort, therefore, for gFOBT and FIT includes 10 screening rounds.

^bCRC detected at surveillance among those with intermediate/high-risk adenomas found at screening.

^cEach incremental value compares values for that strategy with common baseline of no screening.