Table 4. Lifetime ratesa per 100 000 population of screening-related endoscopic proceduresb, and associated complicationsc, for the core screening scenarios.

	Endoscopic procedures			Complications
Scenario	Flexible sigmoidoscopy	Colonoscopy	Polypectomy	Major bleedingd	Bowel perforation	Deaths due to perforation
gFOBT at 55–74 years	—	3386	1215	12	5	0.26
FIT at 55–74 years	—	34 632	9486	132	57	3.00
FSIG once at 60 years	40 177	2543	2487	22	5	0.25

Abbreviations: FIT=faecal immunochemical test; FSIG=flexible sigmoidoscopy; gFOBT=guaiac-based faecal occult blood test.

^aOver the entire lifetime of the cohort, therefore, for gFOBT and FIT includes 10 screening rounds.

^bRelated to screening, diagnosis, or surveillance.

^cComplications associated with diagnostic and surveillance colonoscopy and, where relevant, FSIG.

^dMajor abdominal bleeding, requiring admission or intervention.