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. 2011 Dec 20;1(12):e64. doi: 10.1038/tp.2011.61

Figure 4.

Figure 4

Histone H3K9K14 is hypoacetylated at the promoter regions of genes in young subjects with schizophrenia and associated with decreased gene expression levels. (a) ChIP-qPCR assays were performed on young and old subjects with schizophrenia and age-matched controls (group 2; n=32 subjects in total), measuring ac-H3K9K14 levels at the promoter regions of the indicated genes (UniGene IDs). Asterisks denote significant differences in ac-H3K9K14 levels, as determined by Student's t-test: *, P<0.05, +, P<0.08. (b) Significant differences in microarray expression values were determined by ANOVA as described in Materials and methods; *, P<0.05, **, P<0.01.