Table 1. Summary of genes selected for this study.

Gene ID	Gene description	Cell type association a	Function	SCZ b	SCZ c	BP c
GAD1	Glutamic acid decarboxylase 1	Neuron	GABAergic neurotransmission	↓	↓	↓
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	Neuron	Neurotransmitter receptor signaling	↓	↑	↓
RGS4	Regulator of G-protein signaling 4	Neuron		↓	—	↓
TOMM70A	Translocase of outer mitochondrial membrane 70 homolog A	Neuron	Mitochondrial function/import	↓	↓	↓
PPM1E	Protein phosphatase, Mg2+/Mn2+ dependent, 1E	Neuron	Signal transduction	↓	↓	↑
MBP	Myelin basic protein	Oligodendrocyte	Myelination-associated	↓	↓	↓
UGT8	UDP glycosyltransferase 8	Oligodendrocyte	White matter function	↓		↓
H1FNT	H1 histone family, member N	Ubiquitous	Chromatin-related	↓	NP	NP

The arrows designate the direction of the significant gene expression change in schizophrenia (SCZ) or bipolar disorder (BP) from previous microarray studies.

‘–' designates no significant change in expression; NP, indicates not present in the dataset.

^aCell-type specific expression was determined by comparing with transcriptome datasets for astrocytes, neurons and oligodendrocytes, from Cahoy et al.³²

^bFrom Narayan et al.³⁰

^cFrom the Stanley Medical Research Database, >https://www.stanleygenomics.org/ and Kim and Webster.³¹