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Adjusted hazard ratios for the composite outcome of glomerular filtration rate event or end-stage renal disease among age, race, HbA1c, and renin–angiotensin–aldosterone system blockade subgroups. Hazard ratios greater than 1 demonstrate an increased risk for composite outcome with sulfonylurea compared with metformin. ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker.
