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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Bone Miner Res. 2011 Sep;26(9):2151–2160. doi: 10.1002/jbmr.425

Figure 5.

Figure 5

Effect of Botulinum toxin A (BtxA) on biomechanical parameters at the mid diaphysis for wild type (WT) and Gja1 conditional knockout (cKO) three weeks post injection and 19 weeks post injection. Results are expressed as the absolute change from the control limb of each group. A. Second area moment of inertia (MOI) values from mice sacrificed 3 weeks post-injection. a: p < 0.05 versus WT Saline. B. Second area moment of inertia (MOI) for WT and cKO, sacrificed 19 weeks post injection. b: p < 0.05 vs WT Saline. C. Ultimate Force (bone strength) data for mice sacrificed 3 weeks after BtxA injection. a: p < 0.05 vs WT Saline. D. Ultimate force (bone strength) data for mice sacrificed 19 weeks post-injection for WT and cKO mice. There were no significant differences in ultimate force between the BtxA and Saline groups at this later time point. E. Bone stiffness results for WT and cKO mice three weeks post BtxA injection. a: p < 0.05 versus WT Saline; F. Bone stiffness results for WT and cKO mice sacrificed after 19 weeks. b: p < 0.05 vs cKO Saline.