Figure 1. Behavioral testing in exposed and control mice.

The left column displays the data determined in mice at several ages after exposure. The right column demonstrates the cumulative average. To test memory the Standard object recognition memory test was used and a Preference Index (percent of total exploration time spent exploring the new object) shown at 8, 12, and 16 weeks of age. The cumulative mean preference index of the experimental group was 63.0% and the control group 69.9% (*p = 0.003, n = 161). To test hyperactivity we used the Light/Dark box test and display transitions at 12, 15, and 18 weeks of age. The cumulative mean number of transitions in the experimental group was 24.4 and the control group 16.4 (*p = <0.001, n = 141). To test anxiety we measured time spent in the dark at 12, 15, and 18 weeks of age. The cumulative average time spent in the dark in the experimental group was 207 seconds and in the control was 234 seconds (*p < 0.001, n = 141). To measure fear we used the Step down assay and display the time spent on the platform at 12 weeks and adulthood. The cumulative mean time spent on the platform in the experimental group was 16.7 seconds and in the control was 18.5 seconds (p = 0.59, n = 98).