Table 1.
Variable | MMC (n=19) | 5-Fu (n=18) | P-value |
---|---|---|---|
Age (years) | 61.7 ± 18.9 | 48.4 ± 25.5 | 0.082† |
Male sex [N(%)] | 17 (89.5) | 12 (66.7) | 0.124‡ |
Baseline BCVA (LogMAR) | 1.18 ± 0.64 | 0.82 ± 0.64 | 0.097† |
Glaucoma subtype [N(%)] | 0.192‡ | ||
POAG | 5 (26.3) | 2 (11.1) | |
PACG | 7 (36.7) | 5 (27.8) | |
Congenital | 0 (0) | 5 (27.8) | |
PXF | 2 (10.5) | 3 (16.7) | |
Uveitic | 2 (10.5) | 1 (5.6) | |
Pseudophakic | 3 (15.8) | 2 (11.1) | |
Previous surgeries (N) | 1.0 ± 1.2 | 0.7 ± 1.0 | 0.443§ |
Duration of medications before surgery (years) | 5.6 ± 7.2 | 6.0 ± 9.8 | 0.982§ |
Preoperative medications (N) | 2.5 ± 0.7 | 3.2 ± 0.8 | 0.012§ |
Lens status [N(%)] | 0.022* | ||
Phakic | 6 (31.6) | 13 (72.2) | |
Pseudophakic | 13 (68.4) | 5 (27.8) | |
Preoperative IOP (mmHg) | 20.6 ± 8.8 | 25.8 ± 11.4 | 0.129† |
Cup/disc ratio | 87.2 ± 13.6 | 83.1 ± 17.1 | 0.424† |
Interval between surgery and trial (days) | 7.9 ± 5.1 | 9.7 ± 5.6 | 0.265§ |
Type of operation [N(%)] | 0.017‡ | ||
PT+PCIOL | 11 (57.9) | 3 (16.7) | |
Trabeculectomy | 8 (42.1) | 15 (83.3) |
t-test;
Fisher Exact test;
Mann-Whitney test;
chi-square test
MMC, mitomycin-C; 5-FU, 5-fluorouracil; N, number; BCVA, best-corrected visual acuity; POAG, primary open angle glaucoma; PACG, primary angle closure glaucoma; PXF, pseudoexfoliation; IOP, intraocular pressure; PT+PCIOL, combined phacoemulsification and trabeculectomy with posterior chamber intraocular lens implantation