Table 2.

Intraocular pressures and changes from baseline in the two groups

		Group
		MMC (n=19)	5-Fu (n=18)	95% CI of Difference	P-value
Baseline IOP	(mean ± SD)	20.6 ± 8.8	25.8 ± 11.4	−12.1 – 1.61	0.129†
First Day	(mean ± SD)	12.4 ± 6.4	11.5 ± 6.0	−3.3 – 5.1	0.671†
	Change from baseline	−7.3 ± 10.8	−14.4 ± 13.6	−1.4 – 15.4	0.748*
	(change %)	−27.0	−46.3
	P within group†	0.010	<0.001
First Week	(mean ± SD)	10.5 ± 5.3	10.8 ± 8.0	−5.1 – 4.3	0.865†
	Change from baseline	−9.7 ± 11.0	−16.4 ± 11.9	−1.5 – 15.1	0.939*
	(change %)	−36.3	−56.7
	P within group†	0.002	<0.001
Second Week	(mean ± SD)	12.1 ± 5.0	9.9 ± 6.3	−1.8 – 6.05	0.282†
	Change from baseline	−8.1 ± 8.6	−15.9 ± 12.1	0.42 – 15.1	0.181*
	(change %)	−32.4	−56.4
	P within group†	0.001	<0.001
First Month	(mean ± SD)	13.3 ± 4.8	11.7 ± 4.3	−1.5 – 4.8	0.301†
	Change from baseline	−7.6 ± 9.2	−14.1 ± 13.4	−1.5 – 14.3	0.369*
	(change %)	−26.5	−43.9
	P within group†	0.003	0.001
Third Month	(mean ± SD)	12.5 ± 5.0	10.7 ± 4.4	−1.3 – 4.9	0.251†
	Change from baseline	−8.1 ± 8.9	−15.1 ± 12.3	−0.1 – 14.3	0.196*
	(change %)	−30.7	−52.0
	P within group†	0.001	<0.001
Sixth Month	(mean ± SD)	12.9 ± 5.0	11.2 ± 4.3	−1.5 – 4.8	0.285†
	Change from baseline	−7.7 ± 8.9	−14.8 ± 12.1	−0.1 – 14.2	0.189*
	(change %)	−29.0	−50.4
	P within group†	0.001	<0.001
Twelfth Month	(mean ± SD)	13.2 ± 6.1	10.6 ± 4.8	−1.1 – 6.3	0.159†
	Change from baseline	−7.4 ± 10.4	−15.4 ± 12.1	−0.4 – 15.6	0.143*
	(change %)	−25.4	−52.7
	P within group†	0.006	<0.001

^†Unadjusted P-value based on t-test;

^*Adjusted P-value for baseline based on analysis of covariance

MMC, mitomycin-C; 5-FU, 5-fluorouracil; CI, confidence interval; IOP, intraocular pressure; SD, standard deviation