Table 1.

List of the most relevant biologic agents used in ophthalmology.

Name/Commercial name	Indications	Technology	Mechanism of action
Adalimumab/Humira	rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn’s disease	monoclonal antibody	TNF antagonist
Infliximab/Remicade	rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn’s disease	monoclonal antibody	TNF antagonist
Anakinra/Kineret	rheumatoid arthritis	recombinant human interleukin-1 receptor antagonist	Interleukin-1 receptor binder
Daclizumab/Zenapax	prevention of renal transplant rejection	monoclonal antibody	Interleukin-2 receptor binder
Abatacept/Orencia	rheumatoid arthritis	immunoglobulin CTLA-4 fusion protein	T-cell deactivation
Rituximab/MabThera	CD20-positive non-Hodgkins lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis	monoclonal antibody	CD20 antigen binder
Alemtuzumab/Campath-1H	B-cell chronic lymphocytic leukemia (B-CLL)	monoclonal antibody	CD52 antigen binder