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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: J Neurosci Res. 2012 Apr;90(4):743–750. doi: 10.1002/jnr.22819

Figure 3. NAC injection prevents acute induction of apoptotic cell death elicited by MeHg exposure in the P7 hippocampal dentate gyrus.

Figure 3

A: Detection of activated caspase-3 immunoreactivity in the dentate gyrus following MeHg and/or NAC exposure. P7 rats were injected with vehicle, 5.0 µg/gbw MeHg and/or 5×10µg/gbw NAC, sacrificed at 24 hrs and processed for immunostaining. Scale bar = 100 µm. B: Quantification revealed that the MeHg induced increase in caspase-3 positive cell number was completely blocked by NAC. Values are expressed as the means ± sem per section of 9 sections per animal, 3 animals per group. ***, P < 0.001 vs control; ###, P < 0.001 vs MeHg.