Table 1.
Characteristics of the Included Studies
| Author, Year, Country | Study/center Description |
N | Interval Between Biopsy & APRI |
Median/Mean Age, (% male) |
Etiology | Liver Biopsy Description |
Prevalence Significant Fibrosis (Cirrhosis) |
QUADAS Score |
|---|---|---|---|---|---|---|---|---|
| Chrysanthosa,2006, Greece [31] |
Retrospective 2 centers |
205 | same day | 51 ± 13(74.6%) | HBV | ≥ 1.5 cm | 42.33%(23.11%) | 14 |
| Liu Hongbo,2007, China [33] |
Retrospective 5 centers |
444 | ≤ 1 week | Training group30(71%) Validation group28(79%) |
HBV | ≥ 1.0 cm | 30.18%(4.50%) | 14 |
| Giada Sebastiani, 2007, Italy [10] |
Retrospective 2 centers |
110 | same day | 42.6 ± 11.3(72.7%) | HBV | ≥ 1.5 cm | 68.20%(20%) | 14 |
| Beom Kyung Kim 2007, Korea [35] |
Retrospective 6 centers |
346 | same time | 34 ± 14(85.3%) | HBV | 4 mm | 75.4%(22.8%) | 14 |
| W.G. Shin,2008, Korea [32] |
Retrospective 2 centers |
264 | same time | 24(87.1%) | HBV | 17 mm | 53.4%(3.4%) | 14 |
| ChenSheng, Lin 2008, China [34] |
Retrospective 3 centers |
48 | Unclear | 60.4 ± 11.3(74.2%) | HBV | Unclear | 21.70%(40.20%) | 12 |
| Ruidan Zheng, 2008, China [36] |
Retrospective 3 centers |
131 | ≤ 1 week | 34(84.333%) | HBV | ≥ 1.0 cm | 55.126%(8.897%) | 14 |
| Zhongsheng jiang 2008, China [37] |
Retrospective 1 center |
172 | ≤ 1 day | 35(77.3%) | HBV | ≥ 1.5 cm | 83%(15%) | 14 |
| Sheng-Di Wu, 2010, China [7] |
Retrospective 1 center |
78 | Unclear | 32.6 ± 12.3 (84.6%) |
HBV | ≥ 15 mm | 41%(11.5%) | 13 |