Table 1.
Criteria for SIRS and Sepsis syndromes (modified from Dellinger et al [57])
| Syndrome | Criteria | Mortality |
|---|---|---|
| Systemic inflammatory response syndrome (SIRS) any two or more of the following criteria | ▪ HR>90 bpm ▪ RR>20/min or PaCO2< 32 mmHg ▪ WCC< 4 × 109 cells/L or > 12 × 109 cells/L or > 10% immature bands 12,000 ▪ T>38°C or <36°C |
|
| Sepsis | ▪ SIRS + proven infection | 15% |
| Severe sepsis | ▪ Sepsis + failure of one or more organs | 20% |
| Septic shock | ▪ Severe sepsis + cardiovascular failure despite adequate fluid resuscitation (usually SABP <90 mmHg or >40 mmHg from baseline) | 45% |
HR; Heart rate, RR; Respiratory Rate; WCC; White Cell Count; T; Temperature, SIRS; Systemic Inflammatory Response Syndrome, SABP; Systolic Arterial Blood Pressure.