Table 1.
Risk factors for Invasive Candida Infection in children (from [3])
Risk factors for invasive candidiasis | Unadjusted odds ratio | 95% Confidence interval |
---|---|---|
Malignancy | 3.22 | 1.36-7.6 |
Presence of a central venous catheter | 13.4 | 4.8-37.42 |
Presence of a arterial catheter | 1.77 | 1.02-3.06 |
Receipt of total parenteral nutrition | 5.3 | 2.8-10.05 |
Neutropenia within 15 days | 5.58 | 1.12-27.79 |
Non-candidal blood stream infection within 15 days | 2.47 | 1.35-4.52 |
Receipt of antifungal agents within 15 days | 2.86 | 1.44-5.66 |
Receipt of antibiotics within 15 days | 5.44 | 1.87-15.77 |
Parenteral or oral vancomycin during 1-3 days | 2.56 | 1.27-5.16 |
Parenteral or oral vancomycin ≥4 days | 3.17 | 1.73-5.82 |
Extended-spectrum cephalosporins ≥4 days | 2.31 | 1.26-4.22 |
Carbapenems ≥4 days | 3.29 | 1.1-9.89 |
Aminoglycosides | 2.09 | 1.17-3.74 |
Agents covering anaerobic organisms ≥4 daysa | 2.3 | 1.29-4.11 |
aIncluding ampicillin sulbactam, clindamycin, imipenem, meropenem, metronidazole, and ticarcillin-clavulanate