Table 2.
Demographic and clinical characteristics of all subject, stratified by diabetes, enrolled in Genetic and Inflammatory Markers of Sepsis (GenIMS) and Health, Aging, and Body Composition (Health ABC) study
| Variable | GenIMS study (n=1895) |
Health ABC study (n=1645) |
||||
|---|---|---|---|---|---|---|
| All subjects | With diabetes (n=384) |
Without diabetes (n=1511) |
All subjects | With diabetes (n=299) |
Without diabetes (n=1340) |
|
| Demographics | ||||||
| Age, mean (sd, median) | 67.2, (16.8, 72) | 69.3, (14.5, 73) | 66.7 (17.3, 71) | 73.7 (2.8, 74) | 73.7 (2.8, 73) | 73.7 (2.8, 74) |
| Sex, female, n (%) | 910 (48.0) | 177 (46.1) | 733 (48.5) | 766 (46.7) | 132 (44.1) | 634 (47.3) |
| Race, white, n (%) | 1,529 (80.7) | 307 (80) | 1,222 (80.1) | 939 (57.2) | 127 (42.4) | 812 (60.6) |
| Health behaviors | ||||||
| Ever smoked, n (%) | 1,262 (66.6) | 244 (63.5) | 1,018 (67.4) | 997 (60.9) | 183 (61.6) | 814 (60.8) |
| Chronic health conditions | ||||||
| Respiratory disease, n (%) | 718 (37.9) | 148 (38.5) | 570 (37.7) | 320 (24.2) | 64 (27.4) | 256 (19.3) |
| Cardiovascular disease, n (%) | 488 (25.7) | 165 (42.9) | 323 (21.3)* | 438 (27.3) | 97 (35.9) | 341 (25.9)* |
| Chronic kidney disease, n (%) | 92 (4.8)† | 40 (10.4) | 52 (3.4)* | 403 (24.5) | 102 (34.1) | 301 (22.4)* |
| Cancer§, n (%) | 94 (5.0) | 22 (5.7) | 72 (4.8) | - | - | - |
| HIV§, n (%) | 37 (2.0) | 1 (0.3) | 36 (2.4)* | - | - | - |
*
p<0.05 for comparison among subjects with and without diabetes;
†
Chronic kidney disease (CKD) diagnosis was available in 1571 (82.9%) subjects in GenIMS. In the remaining 324 subjects, CKD could not be ruled out based on history and because their plasma creatinine values were elevated on the first day of hospitalization for pneumonia,
§
Health ABC excluded subjects with active cancer and none reported HIV.