Figure 6. IL-17-producing cells were activated rapidly in the lungs of Ft-infected mice.

Four groups of C57BL/6 mice were i.n.-infected with 1 × 10³ CFU of BHI-grown Ft LVS and killed at Days 1, 3, 5, and 7 PI. One group of sham-inoculated mice served as a control. (A) Levels of IL-17A were measured in the lung homogenates by ELISA. (B–F) Lung cells were analyzed for ICCS of IL-17A by flow cytometry. The percentages and total numbers of different cell types producing IL-17A are shown. The values are expressed as mean ± sem from four independent experiments (n=14 total mice/group). *P < 0.05; **P < 0.01; and ***P < 0.001.