Table 1. Total Number of Cells from Whole Lung Expressing Pro- and/or Anti-Inflammatory Cytokines during Early- and Late-Phase Respiratory Tularemia.
Cells | TNF |
IL-10 |
TGF-β |
||||||
---|---|---|---|---|---|---|---|---|---|
Control | Day 2 | Day 6 | Control | Day 2 | Day 6 | Control | Day 2 | Day 6 | |
Neutrophils | 2087 ± 340 | 2295 ± 711 | 231,141 ± 36,087a | 2162 ± 682 | 8180 ± 4370 | 68,120 ± 5956a | 3536 ± 1326 | 13,210 ± 6771 | 37,273 ± 5968a |
naMΦ | 2904 ± 526 | 5019 ± 1210 | 382,143 ± 47,106a | 972 ± 377 | 17,528 ± 4143b | 143,938 ± 13,339a | 4123 ± 786 | 19,119 ± 3526b | 195,646 ± 16,722a |
DCs | 3540 ± 684 | 10,581 ± 2436 | 171,924 ± 15,549a | 844 ± 227 | 4872 ± 1040b | 44,992 ± 6895a | 2862 ± 393 | 10,103 ± 2011b | 149,390 ± 21,525a |
CD3+ T cells | 3003 ± 1363 | 8029 ± 745 | 35,340 ± 7921a | 3139 ± 567 | 17,802 ± 2044a | 3797 ± 679 | 765 ± 270 | 18,935 ± 5168a | 17,009 ± 2878a |
P < 0.001;
P < 0.05.