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. Author manuscript; available in PMC: 2013 Mar 16.
Published in final edited form as: J Mol Biol. 2012 Jan 28;417(1-2):112–128. doi: 10.1016/j.jmb.2012.01.011

Figure 4.

Figure 4

The best fits of titrations of 50 nM pyr-actin-phalloidin with S1 in the presence of TmTn (0.1 μM) using the Hill and McKillop-Geeves models. The titration time courses of four calcium concentrations (pCa 4.6, 5.4, 6.8 and 8.9) are shown as red lines; in all experiments actin concentration was 50 nM and rate S1 injection rate was 1nM/s. The predictions of the Hill model are denoted as green dashed line, whereas the predictions of McK-G (probabilistic and stochastic) model are denoted as blue dotted lines. The backward rate constants of McK-G model are the same as denoted in Fig. 2. A) Predictions of the Hill model and McK-G probabilistic model and B) predictions of the Hill and McK-G stochastic model.