Table 1. Minimal detection times and growth on PAO.
Strain | Minimal Detection Times on PAO | Doubling Time on PAO | |||||
Growth | AMB | ITR | VOR | CAS | ANI | ||
C. albicans 4208 | 40 min | 2 h | 3 h | 4 h | 2 h | 2 h | 57 min |
C. glabrata 1925 | 51 min | 2 h | R 5 h | R 5 h | 2.5 h | 2 h | 69 min |
C. krusei 870 | 90 min | 2.5 h | 5 h | 5.5 h | 2.5 h | 2 h | 81 min |
C. tropicalis 4367 | 87 min | 2.5 h | 5 h | 5 h | 2.5 h | 2 h | 91 min |
For each strain the minimal time to detect growth and the minimal time to detect drug susceptibility was calculated from triplicate time series using 8 µg AMB, VOR or ITR ml−1 or 4 µg CAS or ANI ml−1. Values are the result of triplicate determinations. The variation between such experiments was <12%. R indicates strain was resistant (so time to detection of resistance is given). Lower part of table indicates MIC values.