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. 2012 Mar 16;7(3):e33226. doi: 10.1371/journal.pone.0033226

Table 2. Predicting factors of survival outcome by univariate and multivariate analysis.

Median Univariate Multivariate
Variables (No.) survival HR (95% CI) p-value HR (95% CI) p-value
(month)
Performance status
ECOG ≤ 1 (148) 13.7
ECOG ≥ 2 (128) 5.9 0.43 (0.33∼0.55) <0.01 0.41 (0.29∼0.57) <0.01
Tuberculosis
With TB (52) 11.6
Without TB (224) 8.8 0.61 (0.43∼0.86) <0.01 0.68 (0.48∼0.97) <0.05
Pathological subtype
Squamous cell carcinoma(100) 11.1
Adenocarcinoma (129) 8.4 0.73 (0.51∼1.05) 0.10
NSCLC, undetermined (47) 8.7 0.83 (0.59∼1.17) 0.29
Gender
Female (84) 10.7
Male (192) 8.7 0.83 (0.63∼1.08) 0.16 0.63 (0.48∼0.83) <0.05
Stage
Stage III (109) 12.5
Stage IV (167) 8.2 0.64 (0.50∼0.83) <0.01 0.62 (0.47∼0.80) <0.01
Smoking status
Non-smoker (104) 9.4
Smoker or ex-smoke (172) 9.0 0.91 (0.71∼1.17) 0.47
Treatment
With treatment (204) 11.6
BSC alone (72) 6.6 0.54 (0.41∼0.72) <0.01 0.90 (0.63∼1.30) 0.58

NSCLC: non-small cell lung cancer, HR: hazard ratio, BSC: best supportive care, TB: tuberculosis.