Table 2. Predicting factors of survival outcome by univariate and multivariate analysis.
Median | Univariate | Multivariate | |||
Variables (No.) | survival | HR (95% CI) | p-value | HR (95% CI) | p-value |
(month) | |||||
Performance status | |||||
ECOG ≤ 1 (148) | 13.7 | ||||
ECOG ≥ 2 (128) | 5.9 | 0.43 (0.33∼0.55) | <0.01 | 0.41 (0.29∼0.57) | <0.01 |
Tuberculosis | |||||
With TB (52) | 11.6 | ||||
Without TB (224) | 8.8 | 0.61 (0.43∼0.86) | <0.01 | 0.68 (0.48∼0.97) | <0.05 |
Pathological subtype | |||||
Squamous cell carcinoma(100) | 11.1 | ||||
Adenocarcinoma (129) | 8.4 | 0.73 (0.51∼1.05) | 0.10 | ||
NSCLC, undetermined (47) | 8.7 | 0.83 (0.59∼1.17) | 0.29 | ||
Gender | |||||
Female (84) | 10.7 | ||||
Male (192) | 8.7 | 0.83 (0.63∼1.08) | 0.16 | 0.63 (0.48∼0.83) | <0.05 |
Stage | |||||
Stage III (109) | 12.5 | ||||
Stage IV (167) | 8.2 | 0.64 (0.50∼0.83) | <0.01 | 0.62 (0.47∼0.80) | <0.01 |
Smoking status | |||||
Non-smoker (104) | 9.4 | ||||
Smoker or ex-smoke (172) | 9.0 | 0.91 (0.71∼1.17) | 0.47 | ||
Treatment | |||||
With treatment (204) | 11.6 | ||||
BSC alone (72) | 6.6 | 0.54 (0.41∼0.72) | <0.01 | 0.90 (0.63∼1.30) | 0.58 |
NSCLC: non-small cell lung cancer, HR: hazard ratio, BSC: best supportive care, TB: tuberculosis.