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. 2012 Mar 16;7(3):e33435. doi: 10.1371/journal.pone.0033435

Figure 4. Effects of methionine on the mRNA and protein expression of DNMTs.

Figure 4

(a) The effects of methionine on the mRNA expressional alteration of Dnmts and Mbd2 induced by cocaine-CPP. Data depicted as the relative gene expression level. (b) The effects of methionine on the alteration of DNMT3a and 3b induced by cocaine-CPP. Data depicted as the relative protein expression level. *p<0.05 in comparison with S-S group. Data are expressed as mean±SEM. [S-S: n = 8(Fig. a), n = 10(Fig. b); M-S: n = 7(Fig. a), n = 9(Fig. b); S-C: n = 10(Fig. a), n = 9(Fig. b); M-C: n = 10(Fig. a), n = 8(Fig. b)].