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. 2012 Mar 16;7(3):e33392. doi: 10.1371/journal.pone.0033392

Figure 2. Neutralizing antibodies in mouse, rabbit, and human serum samples.

Figure 2

(A) Sera from two rTV-HIVgp 145-vaccinated mice (▪, ▴) and two naïve mice (□,△). (B) An anti-VTT rabbit serum (▪), together with an unrelated rabbit control serum (□). (C) Sera from two rMVA-HIVgpe-vaccinated human (▪, ▴) and two naïve human (□, △) were tested using the rTV-Fluc neutralization assay. The x-axis indicates serial dilutions of sera, ranging from 1∶30 to 1∶21870. (D) The dynamics of anti-rMVA-HIVgpe antibody titers. Two months after the first survey at 15 days after immunization, anti-rMVA-HIVgpe antibody titers of 27 participants were measured again. The x-axis indicates months after immunization. The y-axis indicates the MVA specific neutralization antibody titers. The dotted line represents the detection limit of the assay. Each data point in A-D represents the average of three experiments.