Table 2. QTDT analysis with age at onset of daily smoking as quantitative variable.
QTDT Total1 | QTDT Orthogonal1 | |||||
SNP | N | without rs169699682 | with rs169699682 | N | without rs169699682 | with rs169699682 |
rs880395 | 1288 | 0.02 | 0.02 | 212 | 0.08 | 0.08 |
rs7164030 | 1289 | 0.02 | 0.02 | 214 | 0.08 | 0.08 |
rs16969968 | 1288 | 0.25 | - | 174 | 0.52 | - |
rs578776 | 1289 | 0.17 | 0.18 | 218 | 0.66 | 0.66 |
rs3743078 | 1289 | 0.17 | 0.19 | 192 | 0.14 | 0.13 |
rs11634351 | 1289 | 0.007 | 0.006 | 188 | 0.03 | 0.04 |
rs17487514 | 1288 | 0.007 | 0.006 | 146 | 0.004 | 0.005 |
rs1996371 | 1288 | 0.003 | 0.002 | 186 | 0.02 | 0.03 |
rs11857532 | 1287 | 0.02 | 0.02 | 245 | 0.02 | 0.02 |
rs922692 | 1288 | 0.003 | 0.003 | 183 | 0.02 | 0.03 |
Age at interview in quartiles, gender, first principal component of stratification (pc1), parental smoking and parental drinking were included as covariates.
Nominal P values are shown uncorrected for multiple testing. The Bonferroni-corrected significance threshold is Pā=ā0.005.